​​​​​​Ariel Fernandez

AI Scientist - Physicist

Books by Ariel Fernandez

​Daruma Institute for Applied Intelligence



The Daruma Institute for Applied Intelligence opened its doors on December 15, 2018 as the research arm of the AF Innovation Consultancy. Its themes are:



After a foundational phase devoted to biophysics applications, the focus has transitioned to mathematical particle physics, artificial quantum conscience and theoretical particle cosmology. The Daruma Institute is currently headed by Ariel Fernández (CSO). It received seed funding from the Alexander von Humboldt Foundation and the Argentine National Research Council and is supported through industrial and academic consultancy contracts. ​​


Ariel Fernández (Ariel Fernández Stigliano) is an Argentinian-American physicist and mathematician currently involved in research and entrepreneurial activities. Ariel Fernández authored eleven books on translational biophysics and AI empowered theoretical physics. His latest book laid the foundational work for a topological field theory that will purportedly unify the dark sector and gravity. Ariel Fernandez has published over 500 papers in professional journals. He also holds several technological patents.


Publications related to the mission of the Institute


Books by Ariel Fernandez


​Ariel Fernández and L. Ridgway Scott: “Advanced modeling reconciles counterintuitive decisions in lead optimization”. Trends in Biotechnology, CELL Press 35, 490-497 (2017).
DOI: http://dx.doi.org/10.1016/j.tibtech.2016.12.003 

 Ariel Fernández: “Making targeted therapy compatible with checkpoint immunotherapy”. Trends in Biotechnology, CELL Press 35, 582-585 (2017).

DOI: http://dx.doi.org/10.1016/j.tibtech.2017.02.008

 Ariel Fernández: “Engineering Tumor Hypersusceptibility to Checkpoint Immunotherapy”. Trends in Cancer, CELL Press 3, 675-677 (2017).
DOI: http://dx.doi.org/10.1016/j.trecan.2017.08.002


Ariel Fernández: “Deep Learning to Therapeutically Target Unreported Complexes”. Trends in Pharmacological Sciences, CELL Press 40, 551-554 (2019). 
DOI: https://doi.org/10.1016/j.tips.2019.04.009



Daruma Institute for  Applied Intelligence

AF Innovation Consultancy

San Andrés de la Sierra 8160, Argentina  

Riverside, CT, 06878, USA
Phone: +1 336 354 8315, +54 9291 447 9734 
Email: ariel@afinnovation.com

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